Training educators and learners in person-centred, solution-orientated coaching approaches may facilitate the development of a learner-centred mindset.Imperial College London developed a Massive Open Online Collections Course (MOOC) in coaching skills for learner-centred conversations.A mixed methodology (post-course survey and semi-structured inte
Background The potential modifiable factors influencing irritable bowel syndrome (IBS) have not been thoroughly documented.We aimed to systematically investigate the modifiable factors associated with IBS, while accounting for the impact of unobserved confounders and coexisting disorders.Methods Genetic correlation and Mendelian randomisation (MR)
It is now generally acknowledged that climate change has wide-ranging biological consequences, potentially leading to impacts on biodiversity.Environmental factors can have diverse and often strong effects on reproduction, with obvious ramifications for population fitness.Nevertheless, reproductive traits are often neglected in conservation conside
The paper describes a developed comprehensive system for molecular-genetic identification of Yersinia pestis strains according to their appurtenance to certain subspecies, biovars, phylo-geographic populations, using realtime PCR (RT-PCR), allele-specific RT-PCR, and multiplex PCR with hybridization fluorescent registration of results on a solid su
Drug-induced cardiotoxicity is a common side effect of drugs in clinical use or under postmarket surveillance and is commonly due to off-target interactions with the cardiac human-ether-a-go-go-related (hERG) potassium channel.Therefore, prioritizing drug candidates based on their hERG blocking potential is a mandatory step in the early preclinical